Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett’s Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium

BACKGROUND: The strong male predominance in oesophageal adenocarcinoma (OAC) and Barrett’s oesophagus (BO) continues to puzzle. Hormonal influence, e.g. oestrogen or oxytocin, might contribute. METHODS: This genetic-epidemiological study pooled 14 studies from three continents, Australia, Europe, an...

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Udgivet i:PLoS One
Main Authors: Lagergren, Katarina, Ek, Weronica E., Levine, David, Chow, Wong-Ho, Bernstein, Leslie, Casson, Alan G., Risch, Harvey A., Shaheen, Nicholas J., Bird, Nigel C., Reid, Brian J., Corley, Douglas A., Hardie, Laura J., Wu, Anna H., Fitzgerald, Rebecca C., Pharoah, Paul, Caldas, Carlos, Romero, Yvonne, Vaughan, Thomas L., MacGregor, Stuart, Whiteman, David, Westberg, Lars, Nyren, Olof, Lagergren, Jesper
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583498/
https://ncbi.nlm.nih.gov/pubmed/26406593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138738
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