Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett’s Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium

BACKGROUND: The strong male predominance in oesophageal adenocarcinoma (OAC) and Barrett’s oesophagus (BO) continues to puzzle. Hormonal influence, e.g. oestrogen or oxytocin, might contribute. METHODS: This genetic-epidemiological study pooled 14 studies from three continents, Australia, Europe, an...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lagergren, Katarina, Ek, Weronica E., Levine, David, Chow, Wong-Ho, Bernstein, Leslie, Casson, Alan G., Risch, Harvey A., Shaheen, Nicholas J., Bird, Nigel C., Reid, Brian J., Corley, Douglas A., Hardie, Laura J., Wu, Anna H., Fitzgerald, Rebecca C., Pharoah, Paul, Caldas, Carlos, Romero, Yvonne, Vaughan, Thomas L., MacGregor, Stuart, Whiteman, David, Westberg, Lars, Nyren, Olof, Lagergren, Jesper
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583498/
https://ncbi.nlm.nih.gov/pubmed/26406593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138738
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