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Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci

The growing availability of high-quality genomic annotation has increased the potential for mechanistic insights when the specific variants driving common genome-wide association signals are accurately localized. A range of fine-mapping strategies have been advocated, and specific successes reported...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: van de Bunt, Martijn, Cortes, Adrian, Brown, Matthew A., Morris, Andrew P., McCarthy, Mark I.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583479/
https://ncbi.nlm.nih.gov/pubmed/26406328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005535
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