Fine-mapping inflammatory bowel disease loci to single variant resolution

The inflammatory bowel diseases (IBD) are chronic gastrointestinal inflammatory disorders that affect millions worldwide. Genome-wide association studies have identified 200 IBD-associated loci, but few have been conclusively resolved to specific functional variants. Here we report fine-mapping of 9...

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Foilsithe in:Nature
Main Authors: Huang, Hailiang, Fang, Ming, Jostins, Luke, Mirkov, Maša Umićević, Boucher, Gabrielle, Anderson, Carl A, Andersen, Vibeke, Cleynen, Isabelle, Cortes, Adrian, Crins, François, D'Amato, Mauro, Deffontaine, Valérie, Dimitrieva, Julia, Docampo, Elisa, Elansary, Mahmoud, Farh, Kyle Kai-How, Franke, Andre, Gori, Ann-Stephan, Goyette, Philippe, Halfvarson, Jonas, Haritunians, Talin, Knight, Jo, Lawrance, Ian C, Lees, Charlie W, Louis, Edouard, Mariman, Rob, Meuwissen, Theo, Mni, Myriam, Momozawa, Yukihide, Parkes, Miles, Spain, Sarah L, Théâtre, Emilie, Trynka, Gosia, Satsangi, Jack, van Sommeren, Suzanne, Vermeire, Severine, Xavier, Ramnik J, Weersma, Rinse K, Duerr, Richard H, Mathew, Christopher G, Rioux, John D, McGovern, Dermot PB, Cho, Judy H, Georges, Michel, Daly, Mark J, Barrett, Jeffrey C
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511510/
https://ncbi.nlm.nih.gov/pubmed/28658209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22969
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