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Oncogenic activity of BIRC2 and BIRC3 mutants independent of nuclear factor-κB-activating potential
BIRC2 and BIRC3 are closely related members of the inhibitor of apoptosis (IAP) family of proteins and play pivotal roles in regulation of nuclear factor-κB (NF-κB) signaling and apoptosis. Copy number loss for and somatic mutation of BIRC2 and BIRC3 have been frequently detected in lymphoid maligna...
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| Publicado no: | Cancer Sci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582982/ https://ncbi.nlm.nih.gov/pubmed/26094954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12726 |
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