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Cancer‐associated missense mutations of caspase‐8 activate nuclear factor‐κB signaling

Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with a 5‐year survival rate of ~50%. With the use of a custom cDNA‐capture system coupled with massively parallel sequencing, we have now investigated transforming mechanisms for this malignancy. The cDNAs of cancer‐related genes...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ando, Mizuo, Kawazu, Masahito, Ueno, Toshihide, Fukumura, Kazutaka, Yamato, Azusa, Soda, Manabu, Yamashita, Yoshihiro, Choi, Young L., Yamasoba, Tatsuya, Mano, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657200/
https://ncbi.nlm.nih.gov/pubmed/23659359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12191
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