Inactivating mutations and hypermethylation of the NKX2‐1/TTF‐1 gene in non‐terminal respiratory unit‐type lung adenocarcinomas

The major driver mutations of lung cancer, EGFR mutations and EML4‐ALK fusion, are mainly detected in terminal respiratory unit (TRU)‐type lung adenocarcinomas, which typically show lepidic and/or papillary patterns, but are rarely associated with a solid or invasive mucinous morphology. In order to...

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Publicat a:Cancer Sci
Autors principals: Matsubara, Daisuke, Soda, Manabu, Yoshimoto, Taichiro, Amano, Yusuke, Sakuma, Yuji, Yamato, Azusa, Ueno, Toshihide, Kojima, Shinya, Shibano, Tomoki, Hosono, Yasuyuki, Kawazu, Masahito, Yamashita, Yoshihiro, Endo, Shunsuke, Hagiwara, Koichi, Fukayama, Masashi, Takahashi, Takashi, Mano, Hiroyuki, Niki, Toshiro
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581515/
https://ncbi.nlm.nih.gov/pubmed/28677170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13313
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