Inactivating mutations and hypermethylation of the NKX2‐1/TTF‐1 gene in non‐terminal respiratory unit‐type lung adenocarcinomas

The major driver mutations of lung cancer, EGFR mutations and EML4‐ALK fusion, are mainly detected in terminal respiratory unit (TRU)‐type lung adenocarcinomas, which typically show lepidic and/or papillary patterns, but are rarely associated with a solid or invasive mucinous morphology. In order to...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Matsubara, Daisuke, Soda, Manabu, Yoshimoto, Taichiro, Amano, Yusuke, Sakuma, Yuji, Yamato, Azusa, Ueno, Toshihide, Kojima, Shinya, Shibano, Tomoki, Hosono, Yasuyuki, Kawazu, Masahito, Yamashita, Yoshihiro, Endo, Shunsuke, Hagiwara, Koichi, Fukayama, Masashi, Takahashi, Takashi, Mano, Hiroyuki, Niki, Toshiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581515/
https://ncbi.nlm.nih.gov/pubmed/28677170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13313
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