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Inactivating mutations and hypermethylation of the NKX2‐1/TTF‐1 gene in non‐terminal respiratory unit‐type lung adenocarcinomas

The major driver mutations of lung cancer, EGFR mutations and EML4‐ALK fusion, are mainly detected in terminal respiratory unit (TRU)‐type lung adenocarcinomas, which typically show lepidic and/or papillary patterns, but are rarely associated with a solid or invasive mucinous morphology. In order to...

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Bibliografiska uppgifter
I publikationen:Cancer Sci
Huvudupphovsmän: Matsubara, Daisuke, Soda, Manabu, Yoshimoto, Taichiro, Amano, Yusuke, Sakuma, Yuji, Yamato, Azusa, Ueno, Toshihide, Kojima, Shinya, Shibano, Tomoki, Hosono, Yasuyuki, Kawazu, Masahito, Yamashita, Yoshihiro, Endo, Shunsuke, Hagiwara, Koichi, Fukayama, Masashi, Takahashi, Takashi, Mano, Hiroyuki, Niki, Toshiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581515/
https://ncbi.nlm.nih.gov/pubmed/28677170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13313
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