Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures

Decreased cell-substratum adhesion is crucially involved in metastasis. Previous studies demonstrated that lung cancer with floating cell clusters in histology is more likely to develop metastasis. In the present study, we investigated whether cancer cells in long-term, three-dimensional low attachm...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nakano, Tomoyuki, Kanai, Yoshihiko, Amano, Yusuke, Yoshimoto, Taichiro, Matsubara, Daisuke, Shibano, Tomoki, Tamura, Tomoko, Oguni, Sachiko, Katashiba, Shizuka, Ito, Takeshi, Murakami, Yoshinori, Fukayama, Masashi, Murakami, Takashi, Endo, Shunsuke, Niki, Toshiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546599/
https://ncbi.nlm.nih.gov/pubmed/28786996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181342
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