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GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSCs) are a naturally occurring immune regulatory population associated with inhibition of ongoing inflammatory responses. In vitro generation of MDSCs from bone marrow has been shown to enhance survival in an acute model of lethal graft-versus-host disease (GVHD)....

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發表在:Blood
Main Authors: Koehn, Brent H., Apostolova, Petya, Haverkamp, Jessica M., Miller, Jeffrey S., McCullar, Valarie, Tolar, Jakub, Munn, David H., Murphy, William J., Brickey, Willie June, Serody, Jonathan S., Gabrilovich, Dmitry I., Bronte, Vincenzo, Murray, Peter J., Ting, Jenny P.-Y., Zeiser, Robert, Blazar, Bruce R.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582338/
https://ncbi.nlm.nih.gov/pubmed/26265697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-634691
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