GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSCs) are a naturally occurring immune regulatory population associated with inhibition of ongoing inflammatory responses. In vitro generation of MDSCs from bone marrow has been shown to enhance survival in an acute model of lethal graft-versus-host disease (GVHD)....

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Koehn, Brent H., Apostolova, Petya, Haverkamp, Jessica M., Miller, Jeffrey S., McCullar, Valarie, Tolar, Jakub, Munn, David H., Murphy, William J., Brickey, Willie June, Serody, Jonathan S., Gabrilovich, Dmitry I., Bronte, Vincenzo, Murray, Peter J., Ting, Jenny P.-Y., Zeiser, Robert, Blazar, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582338/
https://ncbi.nlm.nih.gov/pubmed/26265697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-634691
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