Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1–dependent mechanism that is up-regulated by interleukin-13

Myeloid-derived suppressor cells (MDSCs) are a well-defined population of cells that accumulate in the tissue of tumor-bearing animals and are known to inhibit immune responses. Within 4 days, bone marrow cells cultured in granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimu...

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Bibliografiska uppgifter
Huvudupphovsmän: Highfill, Steven L., Rodriguez, Paulo C., Zhou, Qing, Goetz, Christine A., Koehn, Brent H., Veenstra, Rachelle, Taylor, Patricia A., Panoskaltsis-Mortari, Angela, Serody, Jonathan S., Munn, David H., Tolar, Jakub, Ochoa, Augusto C., Blazar, Bruce R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2010
Ämnen:
Transplantation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031417/
https://ncbi.nlm.nih.gov/pubmed/20807889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-287839
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