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Structure-Based Design of Dendritic Peptide Bolaamphiphiles for siRNA Delivery

[Image: see text] Development of safe and effective delivery vectors is a critical challenge for the application of RNA interference (RNAi)-based biotechnologies. In this study we show the rational design of a series of novel dendritic peptide bolaamphiphile vectors that demonstrate high efficiency...

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Pubblicato in:ACS Cent Sci
Autori principali: Zeng, Hanxiang, Johnson, Mark E., Oldenhuis, Nathan J., Tiambeng, Timothy N., Guan, Zhibin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582325/
https://ncbi.nlm.nih.gov/pubmed/26436138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.5b00233
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