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Multivalent dendritic polyglycerolamine with arginine and histidine end groups for efficient siRNA transfection
The success of siRNA-based therapeutics highly depends on a safe and efficient delivery of siRNA into the cytosol. In this study, we post-modified the primary amines on dendritic polyglycerolamine (dPG-NH(2)) with different ratios of two relevant amino acids, namely, arginine (Arg) and histidine (Hi...
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| Publicado no: | Beilstein J Org Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464416/ https://ncbi.nlm.nih.gov/pubmed/26124878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.86 |
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