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Myeloma is characterized by stage specific alterations in DNA methylation that occur early during myelomagenesis

Epigenetic changes play important roles in carcinogenesis and influence initial steps in neoplastic transformation by altering genome stability and regulating gene expression. To characterize epigenomic changes during the transformation of normal plasma cells to myeloma, we modified the HELP assay t...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Immunol
Main Authors: Heuck, Christoph J., Mehta, Jayesh, Bhagat, Tushar, Gundabolu, Krishna, Yu, Yiting, Khan, Shahper, Chrysofakis, Grigoris, Schinke, Carolina, Tariman, Joseph, Vickrey, Eric, Pulliam, Natalie, Nischal, Sangeeta, Zhou, Li, Bhattacharya, Sanchari, Meagher, Richard, Hu, Caroline, Maqbool, Shahina, Suzuki, Masako, Parekh, Samir, Reu, Frederic, Steidl, Ulrich, Greally, John, Verma, Amit, Singhal, Seema B.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581585/
https://ncbi.nlm.nih.gov/pubmed/23408834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202493
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