Myeloma is characterized by stage specific alterations in DNA methylation that occur early during myelomagenesis

Epigenetic changes play important roles in carcinogenesis and influence initial steps in neoplastic transformation by altering genome stability and regulating gene expression. To characterize epigenomic changes during the transformation of normal plasma cells to myeloma, we modified the HELP assay t...

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Publicado no:J Immunol
Main Authors: Heuck, Christoph J., Mehta, Jayesh, Bhagat, Tushar, Gundabolu, Krishna, Yu, Yiting, Khan, Shahper, Chrysofakis, Grigoris, Schinke, Carolina, Tariman, Joseph, Vickrey, Eric, Pulliam, Natalie, Nischal, Sangeeta, Zhou, Li, Bhattacharya, Sanchari, Meagher, Richard, Hu, Caroline, Maqbool, Shahina, Suzuki, Masako, Parekh, Samir, Reu, Frederic, Steidl, Ulrich, Greally, John, Verma, Amit, Singhal, Seema B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581585/
https://ncbi.nlm.nih.gov/pubmed/23408834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202493
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