Metabolic mapping of A(3) adenosine receptor agonist MRS5980

(1S,2R,3S,4R,5S)-4-(2-((5-Chlorothiophen-2-yl)ethynyl)-6-(methylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide (MRS5980) is an A(3)AR selective agonist containing multiple receptor affinity- and selectivity-enhancing modifications and a therapeutic candidate drug for...

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Publicado no:Biochem Pharmacol
Main Authors: Fang, Zhong-Ze, Tosh, Dilip K., Tanaka, Naoki, Wang, Haina, Krausz, Kristopher W., O'Connor, Robert, Jacobson, Kenneth A., Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581425/
https://ncbi.nlm.nih.gov/pubmed/26212548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.07.007
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