Metabolic map and bioactivation of the anti-tumour drug noscapine

BACKGROUND AND PURPOSE: Noscapine is a promising anti-tumour agent. The purpose of the present study was to describe the metabolic map and investigate the bioactivation of noscapine. EXPERIMENTAL APPROACH: Ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-o...

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Bibliographic Details
Main Authors: Fang, Zhong-Ze, Krausz, Kristopher W, Li, Fei, Cheng, Jie, Tanaka, Naoki, Gonzalez, Frank J
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504993/
https://ncbi.nlm.nih.gov/pubmed/22671862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02067.x
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