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In Vitro Expansion of CAG, CAA, and Mixed CAG/CAA Repeats

Polyglutamine diseases, including Huntington’s disease and a number of spinocerebellar ataxias, are caused by expanded CAG repeats that are located in translated sequences of individual, functionally-unrelated genes. Only mutant proteins containing polyglutamine expansions have long been thought to...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Figura, Grzegorz, Koscianska, Edyta, Krzyzosiak, Wlodzimierz J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581269/
https://ncbi.nlm.nih.gov/pubmed/26270660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160818741
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