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Membrane Affinity of Platensimycin and Its Dialkylamine Analogs
Membrane permeability is a desired property in drug design, but there have been difficulties in quantifying the direct drug partitioning into native membranes. Platensimycin (PL) is a new promising antibiotic whose biosynthetic production is costly. Six dialkylamine analogs of PL were synthesized wi...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581228/ https://ncbi.nlm.nih.gov/pubmed/26247942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160817909 |
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