Design, Synthesis and Biological Evaluation of Platensimycin Analogs with Varying Degrees of Molecular Complexity

The molecular design, chemical synthesis and biological evaluation of two distinct series of platensimycin analogs with varying degrees of complexity are described. The first series of compounds (analog series I: 6, 15–18, Figure 3) probes the biological importance of the benzoic acid subunit of the...

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Main Authors: Nicolaou, K. C., Stepan, Antonia F., Lister, Troy, Li, Ang, Montero, Ana, Tria, G. Scott, Turner, Craig I., Tang, Yefeng, Wang, Jianhua, Denton, Ross M., Edmonds, David J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669665/
https://ncbi.nlm.nih.gov/pubmed/18771264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8044376
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