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Modeling of Cancer Stem Cell State Transitions Predicts Therapeutic Response
Cancer stem cells (CSCs) possess capacity to both self-renew and generate all cells within a tumor, and are thought to drive tumor recurrence. Targeting the stem cell niche to eradicate CSCs represents an important area of therapeutic development. The complex nature of many interacting elements of t...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4580445/ https://ncbi.nlm.nih.gov/pubmed/26397099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135797 |
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