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Modeling of Cancer Stem Cell State Transitions Predicts Therapeutic Response

Cancer stem cells (CSCs) possess capacity to both self-renew and generate all cells within a tumor, and are thought to drive tumor recurrence. Targeting the stem cell niche to eradicate CSCs represents an important area of therapeutic development. The complex nature of many interacting elements of t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sehl, Mary E., Shimada, Miki, Landeros, Alfonso, Lange, Kenneth, Wicha, Max S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580445/
https://ncbi.nlm.nih.gov/pubmed/26397099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135797
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