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Modeling of Cancer Stem Cell State Transitions Predicts Therapeutic Response

Cancer stem cells (CSCs) possess capacity to both self-renew and generate all cells within a tumor, and are thought to drive tumor recurrence. Targeting the stem cell niche to eradicate CSCs represents an important area of therapeutic development. The complex nature of many interacting elements of t...

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發表在:PLoS One
Main Authors: Sehl, Mary E., Shimada, Miki, Landeros, Alfonso, Lange, Kenneth, Wicha, Max S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580445/
https://ncbi.nlm.nih.gov/pubmed/26397099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135797
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