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Determining Duration of HER2-Targeted Therapy Using Stem Cell Extinction Models
INTRODUCTION: Trastuzumab dramatically improves survival in breast cancer patients whose tumor overexpresses HER2. A subpopulation of cells in human breast tumors has been identified with characteristics of cancer stem cells. These breast cancer stem-like cells (BCSCs) rely on HER2 signaling for sel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532453/ https://ncbi.nlm.nih.gov/pubmed/23284608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046613 |
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