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Association screening of common and rare genetic variants by penalized regression
Motivation: This article extends our recent research on penalized estimation methods in genome-wide association studies to the realm of rare variants. Results: The new strategy is tested on both simulated and real data. Our findings on breast cancer data replicate previous results and shed light on...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025646/ https://ncbi.nlm.nih.gov/pubmed/20693321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq448 |
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