Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity

Enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the primary causes of the epidemics of hand-foot-and-mouth disease (HFMD) that affect more than a million children in China each year and lead to hundreds of deaths. Although there has been progress with vaccines for EV71, the development of a...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Ren, Jingshan, Wang, Xiangxi, Zhu, Ling, Hu, Zhongyu, Gao, Qiang, Yang, Pan, Li, Xuemei, Wang, Junzhi, Shen, Xinliang, Fry, Elizabeth E., Rao, Zihe, Stuart, David I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580203/
https://ncbi.nlm.nih.gov/pubmed/26269176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01102-15
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