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Intermonomer Interactions in Hemagglutinin Subunits HA1 and HA2 Affecting Hemagglutinin Stability and Influenza Virus Infectivity

Influenza virus hemagglutinin (HA) mediates virus entry by binding to cell surface receptors and fusing the viral and endosomal membranes following uptake by endocytosis. The acidic environment of endosomes triggers a large-scale conformational change in the transmembrane subunit of HA (HA2) involvi...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Wang, Wei, DeFeo, Christopher J., Alvarado-Facundo, Esmeralda, Vassell, Russell, Weiss, Carol D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580181/
https://ncbi.nlm.nih.gov/pubmed/26269180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00939-15
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