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Intermonomer Interactions in Hemagglutinin Subunits HA1 and HA2 Affecting Hemagglutinin Stability and Influenza Virus Infectivity
Influenza virus hemagglutinin (HA) mediates virus entry by binding to cell surface receptors and fusing the viral and endosomal membranes following uptake by endocytosis. The acidic environment of endosomes triggers a large-scale conformational change in the transmembrane subunit of HA (HA2) involvi...
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Published in: | J Virol |
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Main Authors: | , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
American Society for Microbiology
2015
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4580181/ https://ncbi.nlm.nih.gov/pubmed/26269180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00939-15 |
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