Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif

Deletion of Gly-720 and Tyr-721 from a highly conserved GYxxØ trafficking signal in the SIVmac239 envelope glycoprotein cytoplasmic domain, producing a virus termed ΔGY, leads to a striking perturbation in pathogenesis in rhesus macaques (Macaca mulatta). Infected macaques develop immune activation...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Breed, Matthew W., Elser, Samra E., Torben, Workineh, Jordan, Andrea P. O., Aye, Pyone P., Midkiff, Cecily, Schiro, Faith, Sugimoto, Chie, Alvarez-Hernandez, Xavier, Blair, Robert V., Somasunderam, Anoma, Utay, Netanya S., Kuroda, Marcelo J., Pahar, Bapi, Wiseman, Roger W., O'Connor, David H., LaBranche, Celia C., Montefiori, David C., Marsh, Mark, Li, Yuan, Piatak, Michael, Lifson, Jeffrey D., Keele, Brandon F., Fultz, Patricia N., Lackner, Andrew A., Hoxie, James A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580161/
https://ncbi.nlm.nih.gov/pubmed/26223646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01134-15
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker