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STAT4 is required for IL-23 responsiveness in Th17 memory cells and NKT cells
STAT4 is a critical mediator of inflammatory immunity and is required for all known IL-12 biological responses, including the induction of IFN-γ and development of Th1 cells. We demonstrate that IL-23, an IL-12-related cytokine, also requires STAT4 for optimal IL-17 secretion from memory T helper ce...
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| Опубликовано в: : | JAKSTAT |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4580079/ https://ncbi.nlm.nih.gov/pubmed/26413419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21623988.2014.955393 |
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