Doxycycline and therapeutic targeting of the DNA damage response in cancer cells: old drug, new purpose

There is a small proportion of cells within a tumour with self-renewing properties, which is resistant to conventional therapy, and is responsible for tumour initiation, maintenance and metastasis. These cells are known as cancer stem cells (CSCs) or tumour-initiating cells (TICs) [1]. Recent public...

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Vydáno v:Oncoscience
Hlavní autoři: Peiris-Pagès, Maria, Sotgia, Federica, Lisanti, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Perspective
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580062/
https://ncbi.nlm.nih.gov/pubmed/26425660
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