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Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts
Here, we employed a “senolytic” assay system as a screening tool, with the goal of identifying and repurposing FDA-approved antibiotics, for the targeting of the senescent cell population. Briefly, we used two established human fibroblast cell lines (MRC-5 and/or BJ) as model systems to induce senes...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6286845/ https://ncbi.nlm.nih.gov/pubmed/30428454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101633 |
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