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First-in-class candidate therapeutics that target mitochondria and effectively prevent cancer cell metastasis: mitoriboscins and TPP compounds

Cancer stem cells (CSCs) have been proposed to be responsible for tumor recurrence, distant metastasis and drug-resistance, in the vast majority of cancer patients. Therefore, there is an urgent need to identify new drugs that can target and eradicate CSCs. To identify new molecular targets that are...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Ózsvári, Béla, Sotgia, Federica, Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346015/
https://ncbi.nlm.nih.gov/pubmed/32452826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103336
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