Dodecyl-TPP Targets Mitochondria and Potently Eradicates Cancer Stem Cells (CSCs): Synergy With FDA-Approved Drugs and Natural Compounds (Vitamin C and Berberine)

Elevated mitochondrial biogenesis and/or metabolism are distinguishing features of cancer cells, as well as Cancer Stem Cells (CSCs), which are involved in tumor initiation, metastatic dissemination, and therapy resistance. In fact, mitochondria-impairing agents can be used to hamper CSCs maintenanc...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: De Francesco, Ernestina Marianna, Ózsvári, Béla, Sotgia, Federica, Lisanti, Michael P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692486/
https://ncbi.nlm.nih.gov/pubmed/31440463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00615
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