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Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

Here, we devised a new strategy for eradicating cancer stem cells (CSCs), via a “synthetic-metabolic” approach, involving two FDA-approved antibiotics and a dietary vitamin supplement. This approach was designed to induce a “rho-zero-like” phenotype in cancer cells. This strategy effectively results...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Fiorillo, Marco, Tóth, Fanni, Sotgia, Federica, Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520007/
https://ncbi.nlm.nih.gov/pubmed/31002656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101905
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