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Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules
Cytoplasmic dynein is a dimeric AAA(+) motor protein that performs critical roles in eukaryotic cells by moving along microtubules using ATP. Here using cryo-electron microscopy we directly observe the structure of Dictyostelium discoideum dynein dimers on microtubules at near-physiological ATP conc...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Pub. Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4579568/ https://ncbi.nlm.nih.gov/pubmed/26365535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9179 |
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