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Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding
Coupling between ATPase and track-binding sites is essential for molecular motors to move along cytoskeletal tracks. In dynein, these sites are separated by a long coiled-coil stalk which must mediate communication between them, yet the underlying mechanism remains unclear. Here we show that changes...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757048/ https://ncbi.nlm.nih.gov/pubmed/19198589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1555 |
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