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Three-dimensional structure of cytoplasmic dynein bound to microtubules

Cytoplasmic dynein is a large, microtubule-dependent molecular motor (1.2 MDa). Although the structure of dynein by itself has been characterized, its conformation in complex with microtubules is still unknown. Here, we used cryoelectron microscopy (cryo-EM) to visualize the interaction between dyne...

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Bibliographic Details
Main Authors: Mizuno, Naoko, Narita, Akihiro, Kon, Takahide, Sutoh, Kazuo, Kikkawa, Masahide
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409227/
https://ncbi.nlm.nih.gov/pubmed/18093913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710406105
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