Thyroid hormone receptors and resistance to thyroid hormone disorders

Thyroid hormone action is predominantly mediated by thyroid hormone receptors (THRs), which are encoded by the thyroid hormone receptor α (THRA) and thyroid hormone receptor β (THRB) genes. Patients with mutations in THRB present with resistance to thyroid hormone β (RTHβ), which is a disorder chara...

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Bibliographic Details
Published in:Nat Rev Endocrinol
Main Authors: Ortiga-Carvalho, Tânia M., Sidhaye, Aniket R., Wondisford, Fredric E.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578869/
https://ncbi.nlm.nih.gov/pubmed/25135573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrendo.2014.143
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