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Complete Activation of Thyroid Hormone Receptor β by T(3) is Essential for Normal Cochlear Function and Morphology in Mice

Background/Aims: Thyroid hormones (THs) regulate many developmental processes, including the developmental onset of cochlear differentiation and function. TH action is mediated mostly by triiodothyronine (T3) bound to thyroid hormone nuclear receptors (TRs). At positive regulated genes and in the ab...

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Autori principali: Richter, Claus-Peter, Münscher, Adrian, Santana Machado, Danielle, Wondisford, Fredric E., Ortiga-Carvalho, Tania M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709180/
https://ncbi.nlm.nih.gov/pubmed/22178950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000335812
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