טוען...
A thyroid hormone receptor mutation that dissociates thyroid hormone regulation of gene expression in vivo
Resistance to thyroid hormone (RTH) is most often due to point mutations in the β-isoform of the thyroid hormone (TH) receptor (TR-β). The majority of mutations involve the ligand-binding domain, where they block TH binding and receptor function on both stimulatory and inhibitory TH response element...
שמור ב:
| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695112/ https://ncbi.nlm.nih.gov/pubmed/19439650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903227106 |
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