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Naturally Occurring Amino Acids in Helix 10 of the Thyroid Hormone Receptor Mediate Isoform-Specific TH Gene Regulation

Thyroid hormone (TH) action is mediated by the products of two genes, TH receptor (THR)α (THRA) and THRβ (THRB) that encode several closely related receptor isoforms with differing tissue distributions. The vast majority of THR isoform–specific effects are thought to be due to tissue-specific differ...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Pinto, Vitor M. S., Minakhina, Svetlana, Qiu, Shuiqing, Sidhaye, Aniket, Brotherton, Michael P., Suhotliv, Amy, Wondisford, Fredric E.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659674/
https://ncbi.nlm.nih.gov/pubmed/28911178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00314
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