A Direct Comparison of Thyroid Hormone Receptor Protein Levels in Mice Provides Unexpected Insights into Thyroid Hormone Action

Background: Thyroid hormone (TH) action is mediated by three major thyroid hormone receptor (THR) isoforms α1, β1, and β2 (THRA1, THRB1, and THRB2). These THRs and a fourth major but non-TH binding isoform, THRA2, are encoded by two genes Thra and Thrb. Reliable antibodies against all THR isoforms a...

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Vydáno v:Thyroid
Hlavní autoři: Minakhina, Svetlana, Bansal, Sanya, Zhang, Alice, Brotherton, Michael, Janodia, Rucha, De Oliveira, Vanessa, Tadepalli, Srikanth, Wondisford, Fredric E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2020
Témata:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415890/
https://ncbi.nlm.nih.gov/pubmed/32122258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0763
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