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Repression of RNA Polymerase II Transcription by B2 RNA Depends on a Specific Pattern of Structural Regions in the RNA

B2 RNA is a mouse non-coding RNA that binds directly to RNA polymerase II (Pol II) and represses transcription by disrupting critical interactions between the polymerase and promoter DNA. How the structural regions within B2 RNA work together to mediate transcriptional repression is not well underst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Noncoding RNA
Hauptverfasser: Ponicsan, Steven L., Kugel, Jennifer F., Goodrich, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578731/
https://ncbi.nlm.nih.gov/pubmed/26405685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ncrna1010004
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