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Repression of RNA Polymerase II Transcription by B2 RNA Depends on a Specific Pattern of Structural Regions in the RNA

B2 RNA is a mouse non-coding RNA that binds directly to RNA polymerase II (Pol II) and represses transcription by disrupting critical interactions between the polymerase and promoter DNA. How the structural regions within B2 RNA work together to mediate transcriptional repression is not well underst...

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Vydáno v:Noncoding RNA
Hlavní autoři: Ponicsan, Steven L., Kugel, Jennifer F., Goodrich, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578731/
https://ncbi.nlm.nih.gov/pubmed/26405685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ncrna1010004
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