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An Effective Strategy for Stabilizing Minimal Coiled Coil Mimetics

[Image: see text] Coiled coils are a major motif in proteins and orchestrate multimerization of various complexes important for biological processes. Inhibition of coiled coil-mediated interactions has significant biomedical potential. However, general approaches that afford short peptides with defi...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Wuo, Michael G., Mahon, Andrew B., Arora, Paramjit S.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577959/
https://ncbi.nlm.nih.gov/pubmed/26340721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b05525
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