Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics

Protein-protein interactions featuring intricate binding epitopes remain challenging targets for synthetic inhibitors. Interactions of NEMO, a scaffolding protein central to NF-κB signaling, exemplify this challenge. Various regulators are known to interact with different coiled coil regions of NEMO...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sadek, Jouliana, Wuo, Michael G., Rooklin, David, Hauenstein, Arthur, Hong, Seong Ho, Gautam, Archana, Wu, Hao, Zhang, Yingkai, Cesarman, Ethel, Arora, Paramjit S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156456/
https://ncbi.nlm.nih.gov/pubmed/32286300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15576-3
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