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Generating Virtual Patients by Multivariate and Discrete Re-Sampling Techniques

PURPOSE: Clinical Trial Simulations (CTS) are a valuable tool for decision-making during drug development. However, to obtain realistic simulation scenarios, the patients included in the CTS must be representative of the target population. This is particularly important when covariate effects exist...

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Bibliografische gegevens
Gepubliceerd in:Pharm Res
Hoofdauteurs: Teutonico, D., Musuamba, F., Maas, H. J., Facius, A., Yang, S., Danhof, M., Della Pasqua, O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577546/
https://ncbi.nlm.nih.gov/pubmed/25994981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1699-x
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