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Generating Virtual Patients by Multivariate and Discrete Re-Sampling Techniques
PURPOSE: Clinical Trial Simulations (CTS) are a valuable tool for decision-making during drug development. However, to obtain realistic simulation scenarios, the patients included in the CTS must be representative of the target population. This is particularly important when covariate effects exist...
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| Publié dans: | Pharm Res |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer US
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4577546/ https://ncbi.nlm.nih.gov/pubmed/25994981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1699-x |
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