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The transcription factor XBP1 is selectively required for eosinophil differentiation

The transcription factor XBP1 has been linked to the development of highly secretory tissues such as plasma cells and Paneth cells, yet its function in granulocyte maturation has remained unknown. Here we discovered an unexpectedly selective and absolute requirement for XBP1 in eosinophil differenti...

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Publicado en:Nat Immunol
Autores principales: Bettigole, Sarah E., Lis, Raphael, Adoro, Stanley, Lee, Ann-Hwee, Spencer, Lisa A., Weller, Peter F., Glimcher, Laurie H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577297/
https://ncbi.nlm.nih.gov/pubmed/26147683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3225
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