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XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

The unfolded protein response (UPR) is a stress response pathway that is driven by the increased load of unfolded proteins in the endoplasmic reticulum of highly secretory cells such as plasma cells (PCs). X box binding protein 1 (XBP1) is a transcription factor that mediates one branch of the UPR a...

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Autors principals: Todd, Derrick J., McHeyzer-Williams, Louise J., Kowal, Czeslawa, Lee, Ann-Hwee, Volpe, Bruce T., Diamond, Betty, McHeyzer-Williams, Michael G., Glimcher, Laurie H.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757870/
https://ncbi.nlm.nih.gov/pubmed/19752183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090738
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