Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression

MAPKs are activated in response to G protein-coupled receptor (GPCR) stimulation and play essential roles in regulating cellular processes downstream of these receptors. However, very little is known about the reciprocal effect of MAPK activation on GPCRs. To investigate possible crosstalk between t...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Paradis, Justine S., Ly, Stevenson, Blondel-Tepaz, Élodie, Galan, Jacob A., Beautrait, Alexandre, Scott, Mark G. H., Enslen, Hervé, Marullo, Stefano, Roux, Philippe P., Bouvier, Michel
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577186/
https://ncbi.nlm.nih.gov/pubmed/26324936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508836112
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares